Preventive Health
8 min read

How a Fertility Test for Man Really Works (And What It Can Reveal)

Discover what happens during a fertility test for man — and what it can tell you about your reproductive health.
blog-headeer
Written by
Samruddhi
Published on
April 24, 2025

If you're looking up “fertility test for man”, you're in good company. According to the CDC, around 1 in 8 couples in the U.S. face infertility, and male factors play a role in nearly half of those cases. That’s why understanding how these tests work — and what they can reveal — is so important.

In this guide, you’ll learn exactly what to expect during a male fertility exam, what doctors look for, and how your results are interpreted. Whether you’re just curious or actively planning for a family, this article gives you the clarity and facts you need.

Why a Fertility Test for Man Matters

Why a Fertility Test for Man Matters
Why a Fertility Test for Man Matters

Let’s be honest — talking about male fertility isn’t always easy. But if you're trying to have a child, a fertility test for man is one of the smartest steps you can take.

A fertility test helps doctors understand what’s going on with your sperm production. It checks things like sperm count, sperm motility (how sperm move), and sperm quality. These are important because about 50% of infertility cases involve male factors, according to the CDC.

You may think everything's fine. You feel healthy. But sometimes, there are hidden issues — like low sperm count or hormone imbalances — that you can’t feel.

A semen analysis can spot these early. It even tells if your body is making normal sperm, or if there’s a problem with the pituitary gland, which controls hormones.

Dr. Paul Turek, a leading U.S. male fertility specialist, says, “Most men don’t realize how common male infertility is — or that simple tests can lead to fast answers.”


What Happens During a Male Fertility Exam

What Happens During a Male Fertility Exam
What Happens During a Male Fertility Exam

If you’re thinking about a fertility test for man, it’s normal to feel unsure about what comes next. Don’t worry — the process is easier than you might think, and it gives you valuable answers.

A male fertility exam is a simple set of tests that help doctors understand how well your body is making and delivering sperm. It usually includes:

  • A medical history review: Your doctor asks about past health issues, sexual habits, recreational drugs, or anything that might affect fertility.
  • A physical exam: The doctor checks your testicles and supporting structures for things like swollen veins or signs of retrograde ejaculation (when sperm goes backward into the bladder).
  • A semen analysis: This is the most common test. You provide a semen sample, which is tested for sperm count, sperm motility (how well they move), sperm morphology (their shape), and sperm quality overall.
  • A blood test: This checks hormone levels like testosterone and follicle stimulating hormone. These hormones help with sperm production and are controlled by the pituitary gland.
  • In some cases, you may also need genetic tests, scrotal ultrasound, or a testicular biopsy to check for deeper issues like a genetic cause, blocked vas deferens, or low sperm concentration.

Key Types of Male Fertility Tests Explained

Key Types of Male Fertility Tests Explained
Key Types of Male Fertility Tests Explained

1. Semen Analysis: The First and Most Important Test

This is usually the first test a doctor will ask for. Why? Because it gives a full picture of your sperm health.

What it checks:

  • Sperm count – how many sperm are in your semen sample
  • Sperm motility – how well they move
  • Sperm morphology – the shape and size of your sperm
  • Sperm concentration – how packed the sperm are in the fluid
  • Sperm quality – overall health of the sperm

You give a sample (usually through masturbation), and it’s tested in a lab. The lab checks if the sperm are normal sperm and if any white blood cells or problems are present.

Doctors use this info to decide the next steps. Semen culture tests can identify bacterial infections in the semen if white blood cells are elevated.

Dr. Amy Schutt, a reproductive endocrinologist, says: “A semen analysis is the starting point — it tells us if there's even a need for further testing.” (Cleveland Clinic)


2. Genetic Tests: When Something Deeper May Be Going On

Sometimes, the sperm look okay but there’s still no pregnancy. That’s when genetic tests can help.

What it checks:

  • Genetic cause of sperm issues (like missing or damaged chromosomes)
  • Conditions that could affect sperm production or delivery
  • Clues about fertility problems in future children

Doctors may order a blood test to look for things like genetic abnormalities or Y chromosome microdeletions. This can also help before doing any assisted reproductive techniques like IVF or ICSI (intracytoplasmic sperm injection).

Genetic tests can reveal Y chromosome changes related to low sperm concentrations.


3. Anti-Sperm Antibodies Test: When the Body Attacks Its Own Sperm

In rare cases, your own immune system might attack your sperm. Sounds wild, but it happens.

What it checks:

  • If your body makes anti sperm antibodies (proteins that stick to sperm)
  • Whether this stops sperm from swimming or fertilizing eggs

Doctors will test your semen or blood to check for these antibodies. If they’re high, the sperm might not reach the egg, even if everything else looks good.

“In about 5-10% of male infertility cases, immune issues are a hidden factor,” says Mayo Clinic research.


4. Ultrasound Imaging: Look Inside Without Surgery

Ultrasound Imaging: Look Inside Without Surgery
Ultrasound Imaging: Look Inside Without Surgery

An ultrasound is like a camera for your insides — no needles, no cutting. It uses high frequency sound waves to make pictures of your testicles and nearby parts. Scrotal ultrasound uses high-frequency sound waves to visualize the testicles for abnormalities.

What it checks:

  • Blockages in the sperm transport system (like the vas deferens)
  • Signs of swollen veins (called varicoceles)
  • Issues in supporting structures around the testicles
  • Unusual masses or a missing testicle. A surgical procedure called a varicocelectomy may be performed to correct varicoceles that affect fertility.

You just lie down while a small device is rolled over the scrotum. It's quick and painless. This helps doctors find physical problems that might stop sperm delivery or lower your sperm count.

"Scrotal ultrasound is a first-line, non-invasive way to assess male infertility," says Dr. Michael Eisenberg, Stanford Urology.


5. Hormone Blood Tests: Check the Fertility Signals

Your body uses hormones to tell the testicles what to do. If the messages aren’t getting through, it can stop sperm production.

What it checks:

  • Testosterone – the main male hormone
  • Follicle stimulating hormone (FSH) – tells the body to make sperm
  • Luteinizing hormone (LH) – helps produce testosterone
  • Prolactin and thyroid hormones – support balance in your system
  • Other hormones related to metabolism and growth

This is done with a simple blood test. Low or high hormone levels can tell doctors if there’s a problem with your brain's signaling (the pituitary gland) or the testicles themselves.


6. Testicular Biopsy: Last Step for Low or No Sperm

If semen analysis tests show very little or no sperm, doctors might do a testicular biopsy. This sounds scary, but it’s a small surgery — usually done with local anesthesia.

What it checks:

  • Whether your body is producing sperm at all
  • If sperm samples are stuck in the testicles but not coming out
  • If a surgical procedure might help (like vasectomy reversal)

A small piece of tissue is taken from the testicle and checked in a lab. Doctors might even find usable sperm for assisted reproductive techniques, like IVF or intracytoplasmic sperm injection.

Testicular biopsy may be performed to determine normal sperm production and is often used if other tests are inconclusive.


What Your Results Mean: From Sperm Count to Sperm Quality

What Your Results Mean: From Sperm Count to Sperm Quality
What Your Results Mean: From Sperm Count to Sperm Quality

This test isn’t just about whether you have sperm — it’s about whether your sperm are healthy enough to do their job. That means checking how many you have, how they move, and what they look like.

Each number helps doctors figure out if there’s a fertility problem. If the sperm count is low, or if they don’t swim right, it could be a sign of hormonal imbalance, past illness, or even sperm problems caused by lifestyle factors.

Various supplements may show possible benefits for improving sperm count or quality, but evidence is limited.

But keep in mind — one test isn’t the full story. Sperm levels change daily. Your doctor may ask for more semen samples or a second sperm analysis to get a clear view. Sperm count can fluctuate between samples and is usually tested multiple times for accuracy.

What Low Sperm Count Could Mean:

  • Your sperm production is slow or interrupted
  • The sperm present in the sample aren’t healthy or mobile enough
  • A blockage might be stopping sperm from getting out (like retrograde ejaculation)
  • Your hormones produced by the pituitary gland might be off
  • Your body’s temperature, stress, or even lifestyle factors (like recreational drugs or poor sleep) may affect your sperm

Understanding Low Sperm Count: Causes and Implications

What Can Affect Results:

  • Being overweight or under too much stress
  • Exposure to high heat (like hot tubs or laptops)
  • Having a past infection or surgery
  • Genetics or underlying medical conditions that affect the testicles
  • Sperm movement or shape (called morphology) may also be poor

What to Do Next:

  • Ask your doctor about hormone testing, semen analysis tests, or reproductive medicine options
  • Try healthy changes: keep a healthy weight, get sleep, and avoid sexual intercourse right before the test
  • If you're struggling to get your partner pregnant, more thorough testing may help. Lifestyle changes like a healthy diet, sufficient exercise, and avoiding smoking and drinking can help prevent infertility issues.

Less Common Causes of Male Infertility

Less Common Causes of Male Infertility
Less Common Causes of Male Infertility
  1. Retrograde Ejaculation: When Sperm Goes the Wrong Way: Instead of exiting through the penis, semen flows back into the bladder. It can be caused by diabetes, spinal cord injuries, prostate surgery, or certain medications. Clue: “Dry orgasm” even though the man climaxed. Post-ejaculation urinalysis checks for sperm in urine, indicating possible retrograde ejaculation.
  2. Genetic Disorders Beyond the Usual Suspects: Rare mutations like CFTR gene mutation (linked to cystic fibrosis) can block or completely absent the vas deferens (sperm transport tube). These men produce sperm—but it never gets out. Genetic testing is key if sperm is missing but hormones are normal.
  3. Obstruction Without Symptoms: A man may have a physical blockage in the epididymis, vas deferens, or ejaculatory ducts and never know. No pain, no swelling—but no sperm in the semen. Can result from previous infections, trauma, or surgery.
  4. Undescended Testicles (Cryptorchidism) from Childhood: If not corrected early, this condition can cause long-term sperm production issues, even if both testes are present in the scrotum now. Often overlooked unless full reproductive history is taken.
  5. Radiation or Chemical Exposure at Work: Jobs involving radiation, heavy metals (lead, cadmium), pesticides, or industrial solvents can quietly harm fertility. Damage may be gradual and irreversible if exposure is long-term. Occupational history is vital.
  6. Pituitary Gland Disorders: A Brain Link: The pituitary sends signals to make sperm. Tumors, trauma, or hormone imbalances here can shut down sperm production without affecting sexual performance. Blood hormone tests (FSH, LH, prolactin) often reveal the issue.
  7. Medication Side Effects Most Don’t Think About: Some antidepressants, anabolic steroids, chemotherapy drugs, and blood pressure meds can impair sperm count and function. Always ask: “Could this drug affect fertility?”

Could Anti Sperm Antibodies Be Affecting Your Fertility?

  • Sometimes, your body sees your own sperm as a threat. When this happens, it makes something called anti sperm antibodies — proteins that attack sperm instead of helping them.
  • This can make it harder for sperm to move or reach the egg. It might even stop the sperm from fertilizing the female partner’s egg altogether.
  • Doctors check this by testing your semen or blood. It’s part of a fertility test for man when other results, like sperm count or motility, don’t explain the issue.

Advanced Testing and Diagnoses

Advanced Testing and Diagnoses
Advanced Testing and Diagnoses

Genetic tests are done using a simple blood sample. They check for missing genes or changes in your chromosomes — the building blocks of life. Some of these changes can stop your body from making healthy sperm or any sperm at all.

When Genetic Tests Are Recommended for Male Infertility

Sometimes, a basic fertility test for man isn't enough to find the full picture. If your sperm count is very low or there's no sperm in your semen, your doctor may suggest genetic tests. These tests look deeper — at your DNA — to understand the root cause of male infertility.

When You Might Need a Genetic Test:

  • You’ve had more than one sperm analysis showing zero or very low sperm
  • You're an infertile male but have no clear reason why
  • Your doctor suspects a condition like Klinefelter syndrome or a Y-chromosome microdeletion
  • You’re considering assisted reproductive treatments like IVF or ICSI

Hormone Levels: The Hidden Key to Male Fertility

Hormone Levels: The Hidden Key to Male Fertility
Hormone Levels: The Hidden Key to Male Fertility

Hormone Evaluation: Why It Matters for Fertility Health

When most people think of male fertility, their mind jumps to sperm count or motility. But behind those numbers is a complex hormonal network that plays a pivotal role in sperm production, sexual development, and overall reproductive health.

Why Hormone Levels Matter

Hormones are the body’s chemical messengers. In men, several hormones regulate sperm production and sexual function. If any of these hormone levels are out of balance — too high or too low — it can significantly affect fertility without any outward symptoms.

Key hormones include:

  • Follicle Stimulating Hormone (FSH): Stimulates the testes to produce sperm. Low levels may indicate a pituitary gland issue, while high levels can signal testicular damage.
  • Luteinizing Hormone (LH): Triggers testosterone production. Both low and high levels can impact sperm development.
  • Testosterone: Essential for sperm production and sexual function. Low testosterone levels (a condition called hypogonadism) are a common cause of male infertility.
  • Prolactin: Elevated levels may interfere with testosterone and sperm production, potentially pointing to a pituitary disorder.
  • Estradiol (a form of estrogen): Present in small amounts in men; imbalances can harm sperm quality.
  • Thyroid Hormones (TSH, T3, T4): These regulate metabolism, which indirectly influences reproductive hormones and sexual habits.

How Lifestyle and Hormones Affect Fertility

How Lifestyle and Hormones Affect Fertility
How Lifestyle and Hormones Affect Fertility

Your lifestyle and hormones play a big part in what a fertility test for man reveals. Things like stress, poor diet, smoking, and lack of sleep can all affect fertility.

They can lower testosterone, reduce the sperm’s ability to swim, and mess with hormone levels. Smoking leads to a reduction in sperm density and viability.

Doctors often run blood test measures to check how your body’s working. If your hormones are off, your sperm production might slow down.

Sometimes, other factors — even related to your partner’s menstrual cycle — can affect your results. That’s why checking male fertility includes more than just a semen test. Small changes can lead to big improvements.

Hormones Checked in Male Fertility Test

🧪 Common Hormones Checked in a Fertility Blood Test for Man

Hormone What It Does What Abnormal Levels Could Mean
Testosterone Supports sperm production and sexual function Low levels may cause poor sperm quality or reduced libido
FSH (Follicle-Stimulating Hormone) Signals the testes to make sperm Low = pituitary issue; High = testicular damage
LH (Luteinizing Hormone) Triggers testosterone production Imbalance can disrupt sperm development
Prolactin Regulates testosterone production High levels may indicate a pituitary tumor or hormone disruption
Estradiol (Estrogen) Present in small amounts; helps balance male hormones High levels can harm sperm production and lower testosterone
TSH (Thyroid Stimulating Hormone) Controls thyroid function Imbalance may affect metabolism and indirectly fertility
T3 & T4 (Thyroid Hormones) Work with TSH to regulate metabolism and reproductive hormones Imbalances may lower sperm count or affect sperm movement

A fertility test for man is a smart first step if you're planning a family or facing fertility questions. It gives real answers — and often, real solutions. In cases where the male partner cannot conceive, sperm donation or adoption may be recommended.

Don’t wait. A simple test today can help shape your tomorrow.